Hereditary cancer syndromes: a modern paradigm
نویسندگان
چکیده
منابع مشابه
Screening for hereditary cancer syndromes.
Volume 91, Number 2 www.aafp.org/afp American Family Physician 125 Case Scenario My patient’s wife died of pancreatic adenocarcinoma at 35 years of age. After her death, her doctor told my patient that their child might be at increased risk of developing pancreatic cancer. My patient asked if pancreatic screening and genetic testing were available for his eight-year-old daughter. He was referre...
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Prevention offers the most cost-effective long-term strategy for the control of cancer and at least one-third of all malignancies are preventable. A number of strategies have been developed over the last decades to provide opportunities for cancer prevention at different levels: primary prevention by reducing levels of exposure to high risk factors or causative agents, secondary prevention thro...
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Inherited forms of renal cancer are estimated to account for 2%–5% of all kidney cancer (1). Currently, 10 inherited cancer susceptibility syndromes are definitively associated with an increased risk of renal cancer (Table 1) and are described in more detail below. Patients with these inherited syndromes develop kidney cancer at an earlier age; furthermore, the lesions can be multifocal, bilate...
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Gastrointestinal cancer is one of the major causes of death worldwide. Hereditary gastrointestinal cancer syndromes constitute about 5-10% of all cancers. About 20-25% of undiagnosed cases have a possible hereditary component, which is not yet established. In the last few decades, the advance in genomics has led to the discovery of multiple cancer predisposition genes in gastrointestinal cancer...
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Established in 1995, the Hereditary Gastrointestinal Cancer Registry aimed at cancer prevention due to hereditary colorectal cancer syndromes in Hong Kong through early detection, timely treatment, education and ongoing research. This article details the history, structure and work of the Registry. A summary is also provided on the results of various research work conducted by the Registry whic...
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ژورنال
عنوان ژورنال: Problems of Endocrinology
سال: 2020
ISSN: 2308-1430,0375-9660
DOI: 10.14341/probl12366